许丹宁

电子邮件:xdanning212@126.com

通讯地址:广州市海珠区东沙街24号

教研室:临床兽医学教研室


简介:

许丹宁,女,1978年10月生,黑龙江牡丹江人,博士,教授,硕士研究生导师,临床兽医学学科带头人。广东省水禽健康养殖工程技术研究中心主任、首批广州市珠江科技新星、广东省优秀青年教师、仲恺十佳青年教师。长期从事动物营养免疫和动物疫病防控方面的研究工作,主持国家级、省部级和市厅级项目11项,获中国产学研合作创新成果优秀奖(排名第3);主编及参编专著5部,参编教材3本,发表论文100余篇,其中SCI收录50余篇。

 

教育背景:

2010.09 - 2011.01:上海医学遗传研究所      访问学者

2004.09 - 2007.06:东北农业大学临床兽医学   博士

2001.09 - 2004.07:东北农业大学临床兽医学   硕士

1996.09 - 2001.07:东北农业大学动医系      学士

 

工作经历:

2013.12 - 至  今:仲恺农业工程学院   教  授

2011.01 - 2014.07:湖南农业大学      博士后

2009.12 - 2013.11:仲恺农业工程学院   副教授

2007.07 - 2009.11:仲恺农业工程学院   讲  师

 

主讲课程:

中兽医学、兽医外科手术学、兽医外科手术学实验

 

 

研究领域:

动物营养免疫和动物疫病防控


承担科研项目情况:

(1)广东省自然科学基金:热应激雏鸡免疫器官损伤及HSP70/HSP27表达的研究(10451022501005703),2010-2012,主持,结题

(2)广东省科技计划:白术多糖对热应激雏鸡生长与免疫功能调控的研究(2010B020307008)2010-2012,主持,结题

(3)广东省科技计划:猪瘟疫情预测方法及监测预警系统的构建(2011B020313022)2011-2013,主持,结题

(4)广东省农业科技推广专项:免疫增强剂-白术多糖在养猪生产中的推广应用(粤财农【2010】540号) ,2011-2012,主持,结题

(5)广州市珠江科技新星专项:白术多糖对热应激雏鸡TLR4/kB信号通路的活化机制(2011J2200026),2011-2014,主持,结题

(6)广东省高等学校优秀青年教师培养计划项目:白术多糖对雏鹅免疫功能的调控及TLR4信号通路的活化机制(Yq2013098),2014-2017,主持,结题

(7)国家自然科学基金青年项目:基于TLR4信号通路探讨白术多糖增进雏鸡细胞免疫功能的作用机制(31402162),2015-2017,主持,结题

(8)广东省工程技术研究中心:广东省水禽健康养殖工程技术研究中心,主持,结题

(9)广东省科技计划重点项目:水禽主要疫病流行病学调查及快速诊断技术研究(2017B020202010),2017-2019,主持,结题

(10)广东省教育厅基础研究重大项目:PAMK经KCs-TLR4/NF-κB干预CTX雏鹅肝损伤的机制研究(2017KZDXM046),2018-2020,主持,结题

 

代表性论著:

1. Danning Xu, Wanyan Li,Bingxin Li , Yunbo Tian* , Yunmao Huang*. The effect of selenium and polysaccharide of Atractylodes macrocephala Koidz. (PAMK) on endoplasmic reticulum stress and apoptosis in chicken spleen induced by heat stress[J]. RSC Adv, 2017, 7: 7519-7525.

2. NanCao, WanyanLi, BingxinLi,YunboTian, DanningXu*. Transcriptome profiling reveals the immune response of goose T cells under selenium stimuli[J]. Animal Science Journal. 2017,88(12):2001-2009.

3. Bingxin Li, Yang Liu, Wanyan Li, Yunbo Tian, Danning Xu*, Nan Cao*.Effect of Selenium on Ion Profiles and Antioxidant Defense in Mice Livers[J]. Biological Trace Element Research. 2018, 184(1):127-135.

4. Wanyan Li, Danning Xu, Bingxin Li, Nan Cao, Sixuan Guo, Qingyan Jiang*, Yunbo Tian*.The polysaccharide of Atractylodes macrocephala koidz (PAMK) alleviates cyclophosphamidemediated immunosuppression in geese, possibly through novel_mir2 targeting of CTLA4 to upregulate the TCR-NFAT pathway[J]. RSC Adv, 2018, 8: 26837-26848.

5. Li Bingxin, Li Wanyan, Tian Yunbo, Guo Sixuan, Huang Yunmao, Xu Danning*, Cao Nan*. Polysaccharide of Atractylodes macrocephala Koidz Enhances Cytokine Secretion by Stimulating the TLR4–MyD88–NF-κB Signaling Pathway in the Mouse Spleen[J]. Journal of Medicinal Food, 2019, 22(9):937-943.

6. Li Bingxin, Li Wanyan, Tian Yunbo, Guo Sixuan, Qian Long, Xu Danning*, Cao Nan*. Selenium Alleviated Hepatocyte Necrosis and DNA Damage in Cyclophosphamide-treated Geese by Mitigating Oxidative Stress[J]. Biological Trace Element Research, 2020, 193(2): 508-516.

7. Xuelian Xiang†, Nan Cao†, Feiyue Chen, Long Qian, Yifei Wang, Yunmao Huang, Yunbo Tian, Danning Xu*, Wanyan Li*, Polysaccharide of Atractylodes macrocephala Koidz (PAMK) alleviates cyclophosphamide-induced immunosuppression in mice by upregulating CD28/IP3R/PLCγ-1/AP-1/NFAT signal pathway. [J]. Frontiers in Pharmacology, 2020 (11):529657

8. Wanyan Li , Xuelian Xiang, Bingxin Li, Yifei Wang, Long Qian, Yunbo Tian, Yunmao Huang, Danning Xu* , Nan Cao*. PAMK Relieves LPS-Induced Enteritis and Improves Intestinal Flora Disorder in Goslings[J]. Evidence-Based Complementary and Alternative Medicine, 2021:9721353

9. Li Wanyan, Zhou Xiangying, Xu Shiwen, Cao Nan, Li Bingxin, Chen Wenbin, Yang Baohe, Yuan Mingfeng, Xu Danning*. Lipopolysaccharide-induced splenic ferroptosis in goslings was alleviated by polysaccharide of atractylodes macrocephala koidz associated with proinflammatory factors. Poult Sci. 2022,101(5):101725.

10. Sun Zongyi, Li Dejun, Wang Haibin, Ding Yu, Zhang Chun, Wang Shuyue, Wang Xuejiao, Li Bingixn, Xu Danning*. Polysaccharide of Atractylodes macrocephala Koidz(PAMK) protects against DEHP-induced apoptosis in grass carp hepatocytes. Fish Shellfish Immunol. 2023 (134):108587.

11. Chen Feiyue, Li Bingxin, Li Wanyan, Chen Wenbin, Huang Yunmao, Tian Yunbo, Yang Baohe, Yuan Mingfeng, Xu Danning, Cao Nan. Polysaccharide of Atractylodes macrocephala Koidz alleviate lipopolysaccharide-stimulated liver inflammation injury of goslings through miR-223/NLRP3 axis. Poult Sci. 2023 ,102(1):102285.

12. Li Bingxin, Ye Yaqiong, Hong Longsheng, Li Wanyan, Wu Qingru, Liu Wenjun, Ma Yongjiang, Xu Danning*, Li Yugu*. Transcriptome analysis reveals a potential regulatory mechanism of the lnc-5423.6/IGFBP5 axis in the early stages of mouse thymic involution. Acta Biochim Biophys Sin (Shanghai). 2023,55(4):548-560.

13. Zhang Bingqi, Hong Longsheng, Ke Jingfei, Zhong Yueyun, Cao Nan, Li Wanyan, Xu Danning, Tian Yunbo, Huang Yunmao, Chen Wenbin, Li Bingxin. Polysaccharide of Atractylodes macrocephala Koidz alleviate lipopolysaccharide-induced liver injury in goslings via the p53 and FOXO pathways. Poult Sci. 2023 Mar;102(3):102480.

14. 李婉雁,曹楠,田允波,相雪莲,李冰心,黄运茂,许丹宁.白术多糖通过Toll样受体4/核因子-κB信号通路调控雏鸡脾脏淋巴细胞免疫功能.动物营养学报,2019,31(11):5192-5201.

15. 许丹宁,王洪斌,肖建华.基于ARIMA的猪瘟发病率预测模型的建立.中国预防兽医学报,2009,31(05):352-355.


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